The latest report titled “Albendazole Production” by Procurement Resource, a global procurement research and consulting firm, provides an in-depth cost analysis of the production process of Albendazole.
Procurement Resource study is based on the latest prices and other economic data available. It also offers additional analysis of the report with detailed breakdown of all cost components (capital investment details, production cost details, economics for another plant location, dynamic cost model). In addition, the report incorporates the production process with detailed process and material flow, capital investment, operating costs along with financial expenses and depreciation charges.
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Procurement Resource’s detailed report describes the stepwise consumption of material and utilities along with a detailed process flow diagram. Furthermore, the study assesses the latest developments within the industry that might influence Albendazole production cost, looking into capacity expansions, plant turnarounds, mergers, acquisitions, and investments.
Procurement Resource Assessment of Albendazole Production Process:
- From Complex Chemical Reaction Method: This report presents the detailed production methodology and cost analysis of Albendazole industrial production across Albendazole manufacturing plants. The synthesis of albendazole unfolds through several steps, starting with the reaction of 4-chloro-2-nitroaniline with acetic anhydride, yielding 1-acetamido-4-chloro-2-nitrobenzene as an initial intermediate. This compound is then treated with potassium thiocyanate, which introduces a thiocyanate group to form 1-acetamido-2-nitro-4-thiocyanatobenzene. Following this, 1-bromopropane is used to modify the thiocyanate group, and the resulting compound is subjected to reduction, typically with palladium on carbon (Pd/C) and hydrogen gas, leading to the production of albendazole as the end product.
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Product Definition:
Albendazole is a broad-spectrum anthelmintic (anti-worm) medication primarily used to treat a variety of parasitic worm infestations. It belongs to the benzimidazole group of anti-parasitic drugs, which work by inhibiting the microtubule formation of parasitic worms, thereby disrupting their energy metabolism and eventually causing their death. Albendazole is effective against a wide range of parasites, including those responsible for diseases such as hydatid disease (caused by Echinococcus granulosus larvae), neurocysticercosis (caused by Taenia solium larvae), roundworms, hookworms, whipworms, pinworms, and many others. It is administered orally and has the advantage of a wide therapeutic range, making it suitable for both individual treatment and mass drug administration campaigns in areas with high rates of parasitic infections. Its versatility and efficacy in treating numerous parasitic infections make albendazole a cornerstone drug in global efforts to control and eliminate neglected tropical diseases.
Market Drivers:
The market for albendazole is driven by several key factors, primarily the global burden of parasitic worm infections, which remain prevalent in many developing countries due to poor sanitation and limited access to clean water. The increased focus on neglected tropical diseases (NTDs) by international health organizations and governments has led to mass deworming programs, significantly boosting the demand for effective and affordable anthelmintics like albendazole. Additionally, the versatility of albendazole in treating a wide range of parasitic infections makes it a staple in both human and veterinary medicine, expanding its market reach. The growing awareness and initiatives for preventive healthcare and pet care also contribute to its demand. Furthermore, research and development efforts aimed at improving drug formulations and delivery systems for better efficacy and compliance are likely to open new avenues for market growth. Lastly, the global rise in zoonotic diseases has underscored the importance of effective anthelmintics, further propelling the market for albendazole.
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