The latest report titled “Acetazolamide Production” by Procurement Resource, a global procurement research and consulting firm, provides an in-depth cost analysis of the production process of Acetazolamide.
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Procurement Resource study is based on the latest prices and other economic data available. It also offers additional analysis of the report with detailed breakdown of all cost components (capital investment details, production cost details, economics for another plant location, dynamic cost model). In addition, the report incorporates the production process with detailed process and material flow, capital investment, operating costs along with financial expenses and depreciation charges.
Procurement Resource’s detailed report describes the stepwise consumption of material and utilities along with a detailed process flow diagram. Furthermore, the study assesses the latest developments within the industry that might influence Acetazolamide production cost, looking into capacity expansions, plant turnarounds, mergers, acquisitions, and investments.
Procurement Resource Assessment of Acetazolamide Production Process:
- From Complex Chemical Synthesis Method: This report presents the detailed production methodology and cost analysis of Acetazolamide industrial production across Acetazolamide manufacturing plants. The production of acetazolamide follows a detailed and stepwise chemical synthesis pathway. Initially, the process involves a reaction between hydrazine hydrate and ammonium thiocyanate to produce 5-amino-2-mercapto-1,3,4-thiadiazole as an intermediate. This intermediate is then acetylated through a reaction with acetic anhydride, followed by oxidation in the presence of oxygen. Subsequently, the compound undergoes a reaction with ammonia, which introduces a sulfonamide group into the molecule, culminating in the creation of acetazolamide as the final product.
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Product Definition:
Acetazolamide is a diuretic medication that belongs to the class of drugs known as carbonic anhydrase inhibitors. It works by inhibiting the activity of the enzyme carbonic anhydrase, which is involved in regulating the balance of salt and water in the body and the production of certain types of bodily fluids. This action leads to increased excretion of bicarbonate, sodium, water, and potassium through the urine, thereby reducing fluid pressure in certain areas of the body. Acetazolamide is primarily used to treat glaucoma, a condition characterized by increased pressure in the eye, and can also be used to manage fluid retention, epilepsy, and altitude sickness. It helps prevent and reduce the symptoms of altitude sickness by allowing the body to acclimatize to higher altitudes more effectively. Despite its benefits, acetazolamide must be used under medical supervision due to potential side effects and interactions with other medications.
Market Drivers:
The market demand for acetazolamide is driven by its broad range of therapeutic applications, including the treatment of glaucoma, altitude sickness, periodic paralysis, and certain types of epilepsy. The increasing prevalence of glaucoma globally, due to aging populations and higher risk factors such as diabetes, fuels the need for effective intraocular pressure-lowering agents like acetazolamide. Additionally, the growing interest in adventure tourism and the rise in military and research operations at high altitudes have increased the demand for medications that can prevent and treat altitude sickness, further boosting acetazolamide’s market. The drug’s role in managing certain renal conditions and its utility in neurological research for studying cerebrospinal fluid production and brain fluid dynamics also contribute to its market growth. However, market expansion may be moderated by the availability of alternative treatments and the potential for side effects requiring careful prescription and monitoring.
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